Teenager Dan Gosling scored deep into extra time to give Everton a 1-0 win over city rivals Liverpool in their FA Cup fourth-round replay on Wednesday.
Bristol Rovers got the FA Cup fifth round underway with an upset on Saturday when Rickie Lambert's late free kick gave the League One (third division) side a 1-0 win over Championship (second division) Southampton.
A summary of Saturday's matches in the FA Cup.
Everton were knocked out of the FA Cup 1-0 by third division Oldham Athletic in the third round.
A 68th-minute penalty by Cristiano Ronaldo secured a 2-2 draw at Middlesbrough in their FA Cup quarter-final.
Manchester United beat Reading 3-2 in an enthralling FA Cup fifth-round and earn a place in the quarter-finals.
Arsenal had to come from behind after Sergio Aguero scored his 30th goal of the season for City in the 63rd minute, racing away on to a pass from Yaya Toure.
Liverpool thrashed third division Luton Town 5-0 in an FA Cup third-round replay with Steven Gerrard grabbing a hat-trick.
Liverpool drew 1-1 at third division Luton Town and Newcastle United were goalless at Stoke City in the FA Cup fourth round.
The next instalment of Chelsea manager Jose Mourinho's mind games with Manchester City's Manuel Pellegrini and Arsenal's chance for redemption against Liverpool provide the backdrop to a mouth-watering FA Cup fifth round.
Phil Neville scored the decisive spot kick to give Everton a 4-3 penalty shootout win over holders Chelsea after their FA Cup fourth-round replay ended in a 1-1 draw after extra time at Stamford Bridge on Saturday.
Arsenal must not rest on their laurels after successive FA Cup victories and instead use one of the side's 'best squads' to inspire them to Premier League glory next season.
Liverpool beat West Ham United 3-1 on penalties after the teams were level at 3-3 after extra time in the FA Cup final.
Premier League Leeds United suffered the biggest upset of the FA Cup third round when they fell to a 3-0 defeat by fourth-tier Crawley Town on Sunday
Cesc Fabregas came off the bench to score a last-minute penalty to earn 10-times winners Arsenal a 1-1 home draw with Championship (second division) side Leeds United in a pulsating FA Cup third-round match on Saturday.
Roberto Mancini, the King of the Italian Cup, took his first step towards Wembley when his Manchester City side earned a 1-0 third-round FA Cup win at Championship side Middlesbrough on Saturday.
Chelsea defender Branislav Ivanovic will miss Sunday's FA Cup semi-final against Tottenham Hotspur at Wembley after being handed a three-match ban by the Football Association (FA).
Holders Arsenal's long unbeaten run in the FA Cup continued but they were frustrated by stubborn Championship leaders Hull City on Saturday, drawing 0-0 in a dreary fifth-round tie at the Emirates Stadium.
Arsenal crushed Middlesbrough 4-1 while Chelsea ended the challenge of minor League Scarborough with a 1-0 win.
Arsene Wenger was hoping to get a better idea from a scan which Henry was having on a groin injury.
The Arsenal manager is not sure whether the injured striker will be fit for next month's FA Cup final against Manchester United.
Liverpool manager Brendan Rodgers was an immensely proud but competitive dad at Anfield on Sunday as his Premier League side overcame the FA Cup challenge of his son's third tier Oldham Athletic.
Alvaro Negredo and Edin Dzeko scored twice each as Premier League high-fliers Manchester City comprehensively quashed second tier Blackburn Rovers' hopes of causing an FA Cup shock with an emphatic 5-0 third-round replay win on Wednesday.
"Winning the final and scoring two is fantastic," said the prolific Dutch international.
Arsenal are favourites to beat Chelsea in the FA Cup final as they will be motivated to end their season on a high.
Headers by Romelu Lukaku and Nemanja Matic earned Manchester United an unconvincing 2-0 victory over Brighton and Hove Albion in a low-key FA Cup quarter-final played in freezing conditions on Saturday.
Captain Steven Gerrard scored twice to rescue Liverpool from FA Cup embarrassment and lead them into the fourth round after a tricky 2-1 win at fourth tier AFC Wimbledon on Monday.
Chelsea gave departing coach Guus Hiddink the perfect leaving present when they came from behind to beat Everton 2-1 in the FA Cup final at Wembley on Saturday.
FA Cup added another incredible chapter to its proud heritage on Saturday as Chelsea and Manchester City were humbled by supposed inferiors.
Harry Kane's hat-trick turned Tottenham Hotspur's potentially tricky FA Cup fifth-round tie at Championship side Fulham into a Sunday stroll by the River Thames as they won 3-0 at Craven Cottage.
West Ham United eased into the quarter-finals of the FA Cup with a 5-1 romp at second-tier Blackburn Rovers on Sunday.
Manchester United's Zlatan Ibrahimovic came off the bench to score the winner as they recovered from an early deficit to beat Championship strugglers Blackburn Rovers 2-1 away in the FA Cup fifth round on Sunday.
The Pakistan Under-19 team celebrated their dominant 191-run victory over India in the Under-19 Asia Cup final in Dubai by dancing to the viral 'FA9LA' track from the blockbuster Dhurandhar.
Substitute Dirk Kuyt struck two minutes from time to give hosts Liverpool a 2-1 FA Cup fourth-round victory over Manchester United on Saturday with visiting captain Patrice Evra being booed throughout and making a mistake for the winner.
Sheffield United pulled off the first major shock of FA Cup third round weekend when the third-tier English side triumphed 3-0 at Premier League outfit Queens Park Rangers on Sunday.
Premier League Newcastle United's FA Cup hopes floundered on England's south coast for the second year in a row as Championship club Brighton and Hove Albion kicked off third round action with a 2-0 victory on Saturday.
The Premier League's two best teams and two most prolific strikers go head to head in the FA Cup on Saturday when Manchester United take on Arsenal in a huge fifth-round tie at Old Trafford (1715 GMT).
Liverpool striker Andy Carroll headed an 87th minute winner to secure a 2-1 victory over Merseyside rivals Everton in an error-strewn FA Cup semi-final at Wembley Stadium on Saturday.
Benni McCarthy's stunning goal three minutes from time sent Blackburn Rovers into the quarter-finals of the FA Cup after a 1-0 win over Arsenal in a mostly lifeless fifth-round replay on Wednesday.